Showing posts with label FoodAllergies. Show all posts
Showing posts with label FoodAllergies. Show all posts

Friday, October 16, 2026

Medications To Avoid With Strawberries: Doctor’s Warning

Which Medications Should Not Be Combined with Strawberries: Warnings from Doctors

Juicy strawberries, which appear on tables in June, can be dangerous for people taking certain medications. Doctors urge caution, as some substances found in this berry may interact undesirably with medications. Strawberries contain natural components, including vitamin K and salicylates, which can alter the effects of some medications. People taking the following groups of medications should exercise the greatest caution……..Continue reading.

Source: AgroReviews

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Critics:

Some people experience an anaphylactoid reaction to eating strawberries. The most common form of this reaction is oral allergy syndrome, but symptoms may also mimic hay fever or include dermatitis or hives, and, in severe cases, may cause breathing problems. Proteomic studies indicate that the allergen may be tied to a protein for the red anthocyanin biosynthesis expressed in strawberry ripening, named Fra a1.

Homologous proteins are found in birch pollen and apple, suggesting that people may develop cross-reactivity to all three species. White-fruited strawberry cultivars, lacking Fra a1, may be an option for strawberry allergy sufferers. Since they lack a protein necessary for normal ripening by anthocyanin synthesis of red pigments, the mature berries do not turn red like other cultivars.

They ripen but remain white, pale yellow or “golden”, appearing like immature berries; this also has the advantage of making them less attractive to birds. A virtually allergen-free cultivar named ‘Sofar’ is available. Strawberries are often grouped according to their flowering habit. Traditionally, this has consisted of a division between “June-bearing” strawberries, which bear their fruit in the early summer and “ever-bearing” strawberries, which often bear several crops of fruit throughout the season.

 One plant throughout a season may produce 50 to 60 times or roughly once every three days. Strawberries occur in three basic flowering habits: short-day, long-day, and day-neutral. These describe the day-length sensitivity of the plant and the type of photoperiod that induces flower formation. Day-neutral cultivars produce flowers regardless of the photoperiod.

Strawberry cultivars vary widely in size, color, flavor, shape, degree of fertility, season of ripening, liability to disease and constitution of plant. On average, a strawberry has about 200 seeds on its external membrane.Some vary in foliage, while others vary materially in the development of their sexual organs. In most cases, the flowers appear hermaphroditic in structure, but function as either male or female.

In addition to being consumed fresh, strawberries can be frozen or made into jam or preserves, as well as dried and used in prepared foods, such as cereal bars. Strawberries and strawberry flavorings are a popular addition to dairy products, such as strawberry milk, strawberry ice cream, strawberry milkshakes/smoothies and strawberry yogurts. In the United Kingdom, “strawberries and cream” is a popular dessert consumed at the Wimbledon tennis tournament.

Strawberries and cream is also a staple snack in Mexico, usually available at ice cream parlors. In Sweden, strawberries are a traditional dessert served on Midsummer’s Eve. Depending on area, strawberry pie, strawberry rhubarb pie, or strawberry shortcake are also common. In Greece, strawberries may be sprinkled with sugar and then dipped in Metaxa, a brandy, and served as a dessert. In Italy, strawberries are used for various desserts and as a common flavoring for gelato (gelato alla fragola).

Fresh strawberries are used as cocktail garnishes to add flavor and texture to a drink. Polyphenol extracted from strawberries have been used in Kanazawa, Japan, to create melting-resistant popsicles. In 2022, world production of strawberries was 9.6 million tonnes, led by China with 35% of the total and the United States and Turkey as other significant producers (table).

Due to the relatively fragile nature of the strawberry, approximately 35 percent of the $2.2 billion United States crop was spoiled in 2020. This led to an Idaho company planning to launch gene-edited strawberries in the near future in an effort to make them more durable. In the U.S., as of 2021, it cost growers around $35,000 per acre to plant and $35,000 per acre to harvest strawberries, with more durable berries potentially reducing the rate of spoilage.

For purposes of commercial production, plants are propagated from runners and, in general, distributed as either bare root plants or plugs. Cultivation follows one of two general models—annual plasticulture, or a perennial system of matted rows or mounds. Greenhouses produce a small amount of strawberries during the off season. The bulk of modern commercial production uses the plasticulture system.

In this method, raised beds are formed each year, fumigated, and covered with plastic to prevent weed growth and erosion. Plants, usually obtained from northern nurseries, are planted through holes punched in this covering, and irrigation tubing is run underneath. Runners are removed from the plants as they appear, to encourage the plants to put most of their energy into fruit development.

After harvesting, the plastic is removed and the plants are plowed into the ground. Strawberry plants produce more and better fruit when they are young. After a year or two, they decline. Replacing them annually improves yields and enables denser planting. However, this necessitates a longer growing season, for the plants to establish themselves. It also costs more to annually purchase plants, form new mounds, and cover them with (new) plastic.

The other major method retains plants for multiple years. This is most common in colder climates. The plants are grown in rows or on mounds. This method requires lower investment and lower maintenance, overall. Yields are typically lower than in plasticulture. Another method uses a compost sock. Plants grown in compost socks have been shown to produce significantly more flavonoids, anthocyanins, fructose, glucose, sucrose, malic acid, and citric acid than fruit produced in the black plastic mulch or matted row systems.

 Similar results in an earlier study conducted by USDA confirms how compost plays a role in the bioactive qualities of two strawberry cultivars. Strawberries may also be propagated by seed, though this is primarily a hobby activity, and is not widely practiced commercially. A few seed-propagated cultivars have been developed for home use, and research into growing from seed commercially is ongoing.

Seeds (achenes) are acquired either via commercial seed suppliers, or by collecting and saving them from the fruit. Strawberries can also be grown indoors in strawberry pots. Strawberries will not grow indoors in winter unless aided by a combination of blue and red LED lights. In Florida, winter is the natural growing season and harvesting begins in mid-November. The Kashubian strawberry is the first Polish fruit to be given commercial protection under EU law.

In the United States in 2017, the collective commercial production of strawberries, blueberries, raspberries, and blackberries was a $6 billion industry dominated by the California growing and marketing company Driscoll’s. In 2017, strawberries alone were a $3.5 billion market of which 82% was for fresh fruit.

To increase consumer demand in the 21st century, commercial producers of strawberries cultivated them mainly for favorable aroma characteristics similar to those of wild strawberries, in addition to having large size, heart-shape, glossy red exterior, firmness, and slow ripening for long shelf-life favorable to ship by ground transportation from farms to stores nationwide for consumption within two weeks of harvest.

In US and Canadian grocery stores, fresh strawberries are typically sold in plastic clamshells, and are among the top fresh produce items in grocery revenues. One marketing analysis identified strawberries and other berries as a source of “happiness” for consumers.

Seasonal allergies: ‘This is by far the worst I’ve ever felt out of nowhere’ Boston.com 23:39 Mon, 20 May In the last 4 hours

Experts, beekeepers weigh in on local honey for seasonal allergies Cronkite News 22:03 Mon, 20 May In the last 8 hours

Philadelphia is one of the worst cities for summer allergies, report finds NBC10, Pennsylvania 17:55 Mon, 20 May Yesterday

Does Dupixent Help With Food Allergies? Dibesity 05:10 Sun, 19 May unday

Are your seasonal allergies worse this year? Here’s why—plus tips for symptom relief CNBC 18:38 Sat, 18 May Saturday

Long-Term Outcomes Associated With β-Lactam Allergies Journal of American Medical Associations 19:16 Fri, 17 May

2.4m UK adults suffer from food allergies FoodManufacture.co.uk 17:59 Fri, 17 May

Check Your Work: Understanding Food Allergies Drug Topics 15:34 Fri, 17 May

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Wednesday, July 22, 2026

Histamine Intolerance: Causes, Symptoms, and Diagnosis

Histamine intolerance means you have high histamine levels in your body. It can happen if your body cannot break down histamine. It can affect multiple systems in your body, but gastrointestinal symptoms are most common. Histamine intolerance is not a sensitivity to histamine but an indication that you’ve developed too much of it. You can be born with this condition or develop it as a result of your genetics, diet, or medications you take. Learn more about histamine intolerance and what you can to if you have it……Story continues….

By: Kiara Anthony

Source: Healthline

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Critics:

Histamine is an organic nitrogenous compound involved in local immune responses communication, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. Discovered in 1910, histamine has been considered a local hormone (autocoid) because it’s produced without involvement of the classic endocrine glands; however, in recent years, histamine has been recognized as a central neurotransmitter.

Histamine is involved in the inflammatory response and has a central role as a mediator of itching. As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues.

It consists of an imidazole ring attached to an ethylamine chain; under physiological conditions, the amino group of the side-chain is protonated.Most histamine in the body is generated in granules in mast cells and in white blood cells (leukocytes) called basophils. Mast cells are especially numerous at sites of potential injury – the nose, mouth, and feet, internal body surfaces, and blood vessels.

Non-mast cell histamine is found in several tissues, including the hypothalamus region of the brain, where it functions as a neurotransmitter. Another important site of histamine storage and release is the enterochromaffin-like (ECL) cell of the stomach. The most important pathophysiologic mechanism of mast cell and basophil histamine release is immunologic.

These cells, if sensitized by IgE antibodies attached to their membranes, degranulate when exposed to the appropriate antigen. Certain amines and alkaloids, including such drugs as morphine, and curare alkaloids, can displace histamine in granules and cause its release. Antibiotics like polymyxin are also found to stimulate histamine release.

Histamine release occurs when allergens bind to mast-cell-bound IgE antibodies. Reduction of IgE overproduction may lower the likelihood of allergens finding sufficient free IgE to trigger a mast-cell-release of histamine.Although histamine is small compared to other biological molecules (containing only 17 atoms), it plays an important role in the body.

It is known to be involved in 23 different physiological functions. Histamine is known to be involved in many physiological functions because of its chemical properties that allow it to be versatile in binding. It is Coulombic (able to carry a charge), conformational, and flexible. This allows it to interact and bind more easily.

It has been known for more than one hundred years that an intravenous injection of histamine causes a fall in the blood pressure. The underlying mechanism concerns both vascular hyperpermeability and vasodilation. Histamine binding to endothelial cells causes them to contract, thus increasing vascular leak.

It also stimulates synthesis and release of various vascular smooth muscle cell relaxants, such as nitric oxide, endothelium-derived hyperpolarizing factors and other compounds, resulting in blood vessel dilation. These two mechanisms play a key role in the pathophysiology of anaphylaxis.
Increased vascular permeability causes fluid to escape from capillaries into the tissues, which leads to the classic symptoms of an allergic reaction:

A runny nose and watery eyes. Allergens can bind to IgE-loaded mast cells in the nasal cavity’s mucous membranes. This can lead to three clinical responses.Nasal congestion due to vascular engorgement associated with vasodilation and increased capillary permeabilityHistamine is a neurotransmitter that is released from histaminergic neurons which project out of the mammalian hypothalamus.

The cell bodies of these neurons are located in a portion of the posterior hypothalamus known as the tuberomammillary nucleus (TMN). The histamine neurons in this region comprise the brain’s histamine system, which projects widely throughout the brain and includes axonal projections to the cortex, medial forebrain bundle, other hypothalamic nuclei, medial septum, the nucleus of the diagonal band, ventral tegmental area, amygdala, striatum, substantia nigra, hippocampus, thalamus and elsewhere.

The histamine neurons in the TMN are involved in regulating the sleep-wake cycle and promote arousal when activated. The neural firing rate of histamine neurons in the TMN is strongly positively correlated with an individual’s state of arousal. These neurons fire rapidly during periods of wakefulness, fire more slowly during periods of relaxation/tiredness, and stop firing altogether during REM and NREM (non-REM) sleep[citation needed].

As an integral part of the immune system, histamine may be involved in immune system disorders and allergies. Mastocytosis is a rare disease in which there is a proliferation of mast cells that produce excess histamine. Histamine intolerance is a presumed set of adverse reactions (such as flush, itching, rhinitis, etc.) to ingested histamine in food. The mainstream theory accepts that there may exist adverse reactions to ingested histamine, but does not recognize histamine intolerance as a separate condition that can be diagnosed.

The role of histamine in health and disease is an area of ongoing research. For example, histamine is researched in its potential link with migraine episodes, when there is a noted elevation in the plasma concentrations of both histamine and calcitonin gene-related peptide (CGRP). These two substances are potent vasodilators, and have been demonstrated to mutually stimulate each other’s release within the trigeminovascular system, a mechanism that could potentially instigate the onset of migraines.

In patients with a deficiency in histamine degradation due to variants in the AOC1 gene that encodes diamine oxidase enzyme, a diet high in histamine has been observed to trigger migraines, that suggests a potential functional relationship between exogenous histamine and CGRP, which could be instrumental in understanding the genesis of diet-induced migraines.

So that the role of histamine, particularly in relation to CGRP, is a promising area of research for elucidating the mechanisms underlying migraine development and aggravation, especially relevant in the context of dietary triggers and genetic predispositions related to histamine metabolism.

In the last month

What is histamine flushing and what can it tell you?

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